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Crystal Structure of the Herpesvirus Nuclear Egress Complex Provides Insights into Inner Nuclear Membrane Remodeling

Although nucleo-cytoplasmic transport is typically mediated through nuclear pore complexes, herpesvirus capsids exit the nucleus via a unique vesicular pathway. Together, the conserved herpesvirus proteins pUL31 and pUL34 form the heterodimeric nuclear egress complex (NEC), which, in turn, mediates...

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Detalles Bibliográficos
Autores principales: Zeev-Ben-Mordehai, Tzviya, Weberruß, Marion, Lorenz, Michael, Cheleski, Juliana, Hellberg, Teresa, Whittle, Cathy, El Omari, Kamel, Vasishtan, Daven, Dent, Kyle C., Harlos, Karl, Franzke, Kati, Hagen, Christoph, Klupp, Barbara G., Antonin, Wolfram, Mettenleiter, Thomas C., Grünewald, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700048/
https://www.ncbi.nlm.nih.gov/pubmed/26711332
http://dx.doi.org/10.1016/j.celrep.2015.11.008