Two Cases of Sarcoma Arising in Giant Cell Tumor of Bone Treated with Denosumab

Giant cell tumor (GCT) of bone is a generally benign, but often locally aggressive, neoplasm of bone, with a propensity for recurrence. Sarcomatous transformation is rare and typically occurs with a history of recurrences and radiation treatment. Denosumab, an inhibitor of the RANK ligand involved i...

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Detalles Bibliográficos
Autores principales: Broehm, Cory Julian, Garbrecht, Erika L., Wood, Jeff, Bocklage, Therese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700156/
https://www.ncbi.nlm.nih.gov/pubmed/26798348
http://dx.doi.org/10.1155/2015/767198

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