Aspirin and atenolol enhance metformin activity against breast cancer by targeting both neoplastic and microenvironment cells

Metformin can induce breast cancer (BC) cell apoptosis and reduce BC local and metastatic growth in preclinical models. Since Metformin is frequently used along with Aspirin or beta-blockers, we investigated the effect of Metformin, Aspirin and the beta-blocker Atenolol in several BC models. In vitr...

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Detalles Bibliográficos
Autores principales: Talarico, Giovanna, Orecchioni, Stefania, Dallaglio, Katiuscia, Reggiani, Francesca, Mancuso, Patrizia, Calleri, Angelica, Gregato, Giuliana, Labanca, Valentina, Rossi, Teresa, Noonan, Douglas M., Albini, Adriana, Bertolini, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700497/
https://www.ncbi.nlm.nih.gov/pubmed/26728433
http://dx.doi.org/10.1038/srep18673

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