Missense mutation in DISC1 C-terminal coiled-coil has GSK3β signaling and sex-dependent behavioral effects in mice

Disrupted-in-Schizophrenia 1 (DISC1) is a risk factor for schizophrenia and affective disorders. The full-length DISC1 protein consists of an N-terminal ‘head’ domain and a C-terminal tail domain that contains several predicted coiled-coils, structural motifs involved in protein-protein interactions...

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Detalles Bibliográficos
Autores principales: Dachtler, James, Elliott, Christina, Rodgers, R. John, Baillie, George S., Clapcote, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700527/
https://www.ncbi.nlm.nih.gov/pubmed/26728762
http://dx.doi.org/10.1038/srep18748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700527/
https://www.ncbi.nlm.nih.gov/pubmed/26728762
http://dx.doi.org/10.1038/srep18748

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