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Assembly of a novel biosynthetic pathway for gentamicin B production in Micromonospora echinospora

BACKGROUND: Isepamicin is a weakly toxic but highly active aminoglycoside antibiotic derivative of gentamicin B. Gentamicin B is a naturally occurring minor component isolated from Micromonospora echinospora. 2ʹ-NH(2)-containing gentamicin C complex is a dominant compound produced by wild-type M. ec...

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Detalles Bibliográficos
Autores principales:	Ni, Xianpu, Sun, Zhenpeng, Gu, Yawen, Cui, Hao, Xia, Huanzhang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700567/ https://www.ncbi.nlm.nih.gov/pubmed/26729212 http://dx.doi.org/10.1186/s12934-015-0402-6

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