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LmABCB3, an atypical mitochondrial ABC transporter essential for Leishmania major virulence, acts in heme and cytosolic iron/sulfur clusters biogenesis
BACKGROUND: Mitochondria play essential biological functions including the synthesis and trafficking of porphyrins and iron/sulfur clusters (ISC), processes that in mammals involve the mitochondrial ATP-Binding Cassette (ABC) transporters ABCB6 and ABCB7, respectively. The mitochondrion of pathogeni...
Autores principales: | Martínez-García, Marta, Campos-Salinas, Jenny, Cabello-Donayre, María, Pineda-Molina, Estela, Gálvez, Francisco J., Orrego, Lina M., Sánchez-Cañete, María P., Malagarie-Cazenave, Sophie, Koeller, David M., Pérez-Victoria, José M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700571/ https://www.ncbi.nlm.nih.gov/pubmed/26728034 http://dx.doi.org/10.1186/s13071-015-1284-5 |
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