Cargando…

TGF-β1/FGF-2 signaling mediates the 15-HETE-induced differentiation of adventitial fibroblasts into myofibroblasts

BACKGROUND: Pulmonary adventitial fibroblasts (PAFs) are activated under stress stimuli leading to their differentiation into myofibroblasts, which is involved in vessel remodeling. 15-HETE is known as an important factor in vessel remodeling under hypoxia; however, the role of 15-HETE in PAF phenot...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Li, Chen, Yan, Li, Guixia, Chen, Minggang, Huang, Wei, Liu, Yanrui, Li, Yumei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700586/ https://www.ncbi.nlm.nih.gov/pubmed/26729053 http://dx.doi.org/10.1186/s12944-015-0174-3

Ejemplares similares

Transcriptomic changes during TGF-β-mediated differentiation of airway fibroblasts to myofibroblasts
por: Walker, Erin Joanne, et al.
Publicado: (2019)

Sphingosine kinase 1 is required for TGF-β mediated fibroblast-to-myofibroblast differentiation in ovarian cancer
por: Beach, Jessica A., et al.
Publicado: (2015)

MYH9 Inhibition Suppresses TGF-β1-Stimulated Lung Fibroblast-to-Myofibroblast Differentiation
por: Sun, Xionghua, et al.
Publicado: (2021)

Molecular changes during TGF β‐mediated lung fibroblast‐myofibroblast differentiation: implication for glucocorticoid resistance
por: Breton, Jean‐Didier, et al.
Publicado: (2018)

Functions of exogenous FGF signals in regulation of fibroblast to myofibroblast differentiation and extracellular matrix protein expression
por: Sun, Changye, et al.
Publicado: (2022)

Fenofibrate inhibits TGF‐β‐induced myofibroblast differentiation and activation in human lung fibroblasts in vitro
por: Kikuchi, Ryota, et al.
Publicado: (2021)

HMGB1 induces lung fibroblast to myofibroblast differentiation through NF-κB-mediated TGF-β1 release
por: Wang, Qiong, et al.
Publicado: (2017)

Curdione ameliorates bleomycin-induced pulmonary fibrosis by repressing TGF-β-induced fibroblast to myofibroblast differentiation
por: Liu, Peng, et al.
Publicado: (2020)

Curcumin Suppresses TGF-β1-Induced Myofibroblast Differentiation and Attenuates Angiogenic Activity of Orbital Fibroblasts
por: Yu, Wei-Kuang, et al.
Publicado: (2021)

Nintedanib inhibits TGF-β-induced myofibroblast transdifferentiation in human Tenon’s fibroblasts
por: Lin, Xianchai, et al.
Publicado: (2018)

Correction to: Curdione ameliorates bleomycin-induced pulmonary fibrosis by repressing TGF-β-induced fibroblast to myofibroblast differentiation
por: Liu, Peng, et al.
Publicado: (2023)

Mesenchymal stem cells reversibly de-differentiate myofibroblasts to fibroblast-like cells by inhibiting the TGF-β-SMAD2/3 pathway
por: Xu, Ruohao, et al.
Publicado: (2023)

Key role of 15-LO/15-HETE in angiogenesis and functional recovery in later stages of post-stroke mice
por: Wang, Di, et al.
Publicado: (2017)

TGF-β-induced interleukin-6 participates in transdifferentiation of human Tenon’s fibroblasts to myofibroblasts
por: Seong, Gong Je, et al.
Publicado: (2009)

Utility of 15(S)-HETE as a Serological Marker for Eosinophilic Esophagitis
por: Lu, Shaolei, et al.
Publicado: (2018)

Myocardin-Related Transcription Factors-A and -B are Key Regulators of TGF-β1-Induced Fibroblast to Myofibroblast Differentiation
por: Crider, Beverly J., et al.
Publicado: (2011)

Tofacitinib May Inhibit Myofibroblast Differentiation from Rheumatoid-Fibroblast-like Synoviocytes Induced by TGF-β and IL-6
por: Ruscitti, Piero, et al.
Publicado: (2022)

The Role of Focal Adhesion Kinase in the TGF-β-Induced Myofibroblast Transdifferentiation of Human Tenon's Fibroblasts
por: Hong, Samin, et al.
Publicado: (2012)

MEK inhibition prevents TGF-β1-induced myofibroblast transdifferentiation in human tenon fibroblasts
por: Wen, Jiamin, et al.
Publicado: (2019)

Induced pluripotent stem cell-conditioned medium suppresses pulmonary fibroblast-to-myofibroblast differentiation via the inhibition of TGF-β1/Smad pathway
por: Zhou, Yan, et al.
Publicado: (2018)

Aspirin inhibits the production of proangiogenic 15(S)-HETE by platelet cyclooxygenase-1
por: Rauzi, Francesca, et al.
Publicado: (2016)

Lithium Attenuates TGF-β (1)-Induced Fibroblasts to Myofibroblasts Transition in Bronchial Fibroblasts Derived from Asthmatic Patients
por: Michalik, Marta, et al.
Publicado: (2012)

TGF-β-induced activation of conjunctival fibroblasts is modulated by FGF-2 and substratum stiffness
por: Matsumura, Tomoyo, et al.
Publicado: (2020)

Effect of Pirfenidone on TGF-β1-Induced Myofibroblast Differentiation and Extracellular Matrix Homeostasis of Human Orbital Fibroblasts in Graves’ Ophthalmopathy
por: Wu, Shi-Bei, et al.
Publicado: (2021)

Single-walled carbon nanotubes promote rat vascular adventitial fibroblasts to transform into myofibroblasts by SM(22)-α expression
por: Lin, Zhiqing, et al.
Publicado: (2012)

Fibroblast growth factor-2, but not the adipose tissue-derived stromal cells secretome, inhibits TGF-β1-induced differentiation of human cardiac fibroblasts into myofibroblasts
por: Liguori, Tácia Tavares Aquinas, et al.
Publicado: (2018)

Vascular Adventitial Fibroblasts-Derived FGF10 Promotes Vascular Smooth Muscle Cells Proliferation and Migration in vitro and the Neointima Formation in vivo
por: Chen, Yuhan, et al.
Publicado: (2021)

Erratum in: Critical Role of mTORC2-Akt Signaling in TGF-β1-Induced Myofibroblast Differentiation of Human Pterygium Fibroblasts
Publicado: (2021)

Correction: TGF-β-induced activation of conjunctival fibroblasts is modulated by FGF-2 and substratum stiffness
por: Matsumura, Tomoyo, et al.
Publicado: (2021)

FGF-2 enhances fibrogenetic changes in TGF-β2 treated human conjunctival fibroblasts
por: Tsugeno, Yuri, et al.
Publicado: (2022)

TGF-β1/SMOC2/AKT and ERK axis regulates proliferation, migration, and fibroblast to myofibroblast transformation in lung fibroblast, contributing with the asthma progression
por: Wang, Yuebin, et al.
Publicado: (2021)

Ogerin mediated inhibition of TGF-β(1) induced myofibroblast differentiation is potentiated by acidic pH
por: Bell, Tyler J., et al.
Publicado: (2022)

Enhancement of the HIF-1α/15-LO/15-HETE Axis Promotes Hypoxia-Induced Endothelial Proliferation in Preeclamptic Pregnancy
por: Yuan, Dandan, et al.
Publicado: (2014)

Lefty-1 alleviates TGF-β1-induced fibroblast–myofibroblast transdifferentiation in NRK-49F cells
por: Zhang, Lijun, et al.
Publicado: (2015)

Conflicting Roles of 20-HETE in Hypertension and Stroke
por: Shekhar, Shashank, et al.
Publicado: (2019)

Relaxin Prevents Cardiac Fibroblast-Myofibroblast Transition via Notch-1-Mediated Inhibition of TGF-β/Smad3 Signaling
por: Sassoli, Chiara, et al.
Publicado: (2013)

Oxymatrine Inhibits Transforming Growth Factor β1 (TGF-β1)-Induced Cardiac Fibroblast-to-Myofibroblast Transformation (FMT) by Mediating the Notch Signaling Pathway In Vitro
por: Zhao, Linglu, et al.
Publicado: (2018)

TGF beta inhibits HGF, FGF7, and FGF10 expression in normal and IPF lung fibroblasts
por: Correll, Kelly A., et al.
Publicado: (2018)

Smooth muscle FGF/TGFβ cross talk regulates atherosclerosis progression
por: Chen, Pei‐Yu, et al.
Publicado: (2016)

mTORC1 is a key regulator that mediates OGD- and TGFβ1-induced myofibroblast transformation and chondroitin-4-sulfate expression in cardiac fibroblasts
por: Li, Chao, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_pmlehjmik5i1tgqtf53h24pl0b