SHP2 acts both upstream and downstream of multiple receptor tyrosine kinases to promote basal-like and triple-negative breast cancer

INTRODUCTION: Dysregulated receptor tyrosine kinase (RTK) signaling is a common occurrence in basal-like and triple-negative breast cancer (BTBC). As a result, RTK-targeting therapies have been initiated but proved difficult, mainly owing to the multiplicity of dysregulated RTKs. Hence, targeting ma...

Descripción completa

Detalles Bibliográficos
Autores principales: Matalkah, Fatimah, Martin, Elisha, Zhao, Hua, Agazie, Yehenew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700603/
https://www.ncbi.nlm.nih.gov/pubmed/26728598
http://dx.doi.org/10.1186/s13058-015-0659-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700603/
https://www.ncbi.nlm.nih.gov/pubmed/26728598
http://dx.doi.org/10.1186/s13058-015-0659-z

Ejemplares similares