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The structure of a prophenoloxidase (PPO) from Anopheles gambiae provides new insights into the mechanism of PPO activation

BACKGROUND: Phenoloxidase (PO)-catalyzed melanization is a universal defense mechanism of insects against pathogenic and parasitic infections. In mosquitos such as Anopheles gambiae, melanotic encapsulation is a resistance mechanism against certain parasites that cause malaria and filariasis. PO is...

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Detalles Bibliográficos
Autores principales:	Hu, Yingxia, Wang, Yang, Deng, Junpeng, Jiang, Haobo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700666/ https://www.ncbi.nlm.nih.gov/pubmed/26732497 http://dx.doi.org/10.1186/s12915-015-0225-2

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