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Pharmacokinetics of mefloquine and its effect on sulfamethoxazole and trimethoprim steady-state blood levels in intermittent preventive treatment (IPTp) of pregnant HIV-infected women in Kenya

BACKGROUND: Intermittent preventive treatment in pregnancy with sulfadoxine/pyrimethamine is contra-indicated in HIV-positive pregnant women receiving sulfamethoxazole/trimethoprim prophylaxis. Since mefloquine is being considered as a replacement for sulfadoxine/pyrimethamine in this vulnerable pop...

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Detalles Bibliográficos
Autores principales:	Green, Michael, Otieno, Kephas, Katana, Abraham, Slutsker, Laurence, Kariuki, Simon, Ouma, Peter, González, Raquel, Menendez, Clara, ter Kuile, Feiko, Desai, Meghna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700759/ https://www.ncbi.nlm.nih.gov/pubmed/26732683 http://dx.doi.org/10.1186/s12936-015-1049-9

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