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Deficiency of multidrug resistance 2 contributes to cell transformation through oxidative stress
Multidrug resistance 2 (Mdr2), also called adenosine triphosphate-binding cassette B4 (ABCB4), is the transporter of phosphatidylcholine (PC) at the canalicular membrane of mouse hepatocytes, which plays an essential role for bile formation. Mutations in human homologue MDR3 are associated with seve...
Autores principales: | Tebbi, Ali, Levillayer, Florence, Jouvion, Grégory, Fiette, Laurence, Soubigou, Guillaume, Varet, Hugo, Boudjadja, Nesrine, Cairo, Stefano, Hashimoto, Kosuke, Suzuki, Ana Maria, Carninci, Piero, Carissimo, Annamaria, di Bernardo, Diego, Wei, Yu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700935/ https://www.ncbi.nlm.nih.gov/pubmed/26542370 http://dx.doi.org/10.1093/carcin/bgv156 |
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