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Reassessing the Evolutionary History of the 17q21 Inversion Polymorphism

A polymorphic inversion that lies on chromosome 17q21 comprises two major haplotype families (H1 and H2) that not only differ in orientation but also in copy-number. Although the processes driving the spread of the inversion-associated lineage (H2) in humans remain unclear, a selective advantage has...

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Detalles Bibliográficos
Autores principales: Alves, Joao M., Lima, Ana C., Pais, Isa A., Amir, Nadir, Celestino, Ricardo, Piras, Giovanna, Monne, Maria, Comas, David, Heutink, Peter, Chikhi, Lounès, Amorim, António, Lopes, Alexandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700947/
https://www.ncbi.nlm.nih.gov/pubmed/26560338
http://dx.doi.org/10.1093/gbe/evv214