Genome-Wide Analysis of Evolutionary Markers of Human Influenza A(H1N1)pdm09 and A(H3N2) Viruses May Guide Selection of Vaccine Strain Candidates

Here we analyzed whole-genome sequences of 3,969 influenza A(H1N1)pdm09 and 4,774 A(H3N2) strains that circulated during 2009–2015 in the world. The analysis revealed changes at 481 and 533 amino acid sites in proteins of influenza A(H1N1)pdm09 and A(H3N2) strains, respectively. Many of these change...

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Detalles Bibliográficos
Autores principales: Belanov, Sergei S., Bychkov, Dmitrii, Benner, Christian, Ripatti, Samuli, Ojala, Teija, Kankainen, Matti, Kai Lee, Hong, Wei-Tze Tang, Julian, Kainov, Denis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700966/
https://www.ncbi.nlm.nih.gov/pubmed/26615216
http://dx.doi.org/10.1093/gbe/evv240

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