FOXP3(+) Regulatory T Cells in Hepatic Fibrosis and Splenomegaly Caused by Schistosoma japonicum: The Spleen May Be a Major Source of Tregs in Subjects with Splenomegaly

Schistosoma eggs cause chronic liver inflammation and a complex disease characterized by hepatic fibrosis (HF) and splenomegaly (SplM). FOXP3(+) Tregs could regulate inflammation, but it is unclear where these cells are produced and what roles they play in human schistosomiasis. We investigated bloo...

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Detalles Bibliográficos
Autores principales: Romano, Audrey, Hou, Xunya, Sertorio, Mathieu, Dessein, Hélia, Cabantous, Sandrine, Oliveira, Pablo, Li, Jun, Oyegue, Sandrine, Arnaud, Violaine, Luo, Xinsong, Chavanieu, Martine, Mariani, Odette, Sastre, Xavier, Dombey, Anne-Marie, He, Hongbin, Li, Yuesheng, Dessein, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701139/
https://www.ncbi.nlm.nih.gov/pubmed/26731721
http://dx.doi.org/10.1371/journal.pntd.0004306

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