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Human Circulating Antibody-Producing B Cell as a Predictive Measure of Mucosal Immunity to Poliovirus

BACKGROUND: The “gold standard” for assessing mucosal immunity after vaccination with poliovirus vaccines consists in measuring virus excretion in stool after challenge with oral poliovirus vaccine (OPV). This testing is time and resource intensive, and development of alternative methods is a priori...

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Detalles Bibliográficos
Autores principales: Dey, Ayan, Molodecky, Natalie A., Verma, Harish, Sharma, Prashant, Yang, Jae Seung, Saletti, Giulietta, Ahmad, Mohammad, Bahl, Sunil K., Wierzba, Thomas F., Nandy, Ranjan K., Deshpande, Jagadish M., Sutter, Roland W., Czerkinsky, Cecil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701219/
https://www.ncbi.nlm.nih.gov/pubmed/26730586
http://dx.doi.org/10.1371/journal.pone.0146010