Cargando…

Multiple myeloma cell lines and primary tumors proteoma: protein biosynthesis and immune system as potential therapeutic targets

Despite great advance in multiple myeloma (MM) treatment since 2000s, it is still an incurable disease and novel therapies are welcome. Therefore, the purpose of this study was to explore MM plasma cells' (MM-PC) proteome, in comparison with their normal counterparts (derived from palatine tons...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fernando, Rodrigo Carlini, de Carvalho, Fabricio, Mazzotti, Diego Robles, Evangelista, Adriane Feijó, Braga, Walter Moisés Tobias, de Lourdes Chauffaille, Maria, Leme, Adriana Franco Paes, Colleoni, Gisele Wally Braga
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701225/ https://www.ncbi.nlm.nih.gov/pubmed/26807199

Ejemplares similares

Tumor Microenvironment Proteomics: Lessons From Multiple Myeloma
por: Fernando, Rodrigo Carlini, et al.
Publicado: (2021)

Analysis of protein profile expressed on the membrane surface of plasma cells, stromal cells and mononuclear cells from bone marrow microenvironment of multiple myeloma patients by mass spectrometry
por: de Carvalho, Fabricio, et al.
Publicado: (2013)

Transcriptome Analysis of Mesenchymal Stem Cells from Multiple Myeloma Patients Reveals Downregulation of Genes Involved in Cell Cycle Progression, Immune Response, and Bone Metabolism
por: Fernando, Rodrigo Carlini, et al.
Publicado: (2019)

FOXP3 and CTLA4 overexpression in multiple myeloma bone marrow as a sign of accumulation of CD4(+) T regulatory cells
por: Braga, Walter Moises Tobias, et al.
Publicado: (2014)

Plasma cell leukemia with t(11;14)(q13;q32) simulating lymphoplasmacytic lymphoma – a diagnostic challenge solved by flow cytometry
por: Loureiro, Aleyde Diniz, et al.
Publicado: (2017)

Proteasome and heat shock protein 70 (HSP70) inhibitors as therapeutic alternative in multiple myeloma
por: Eugênio, Angela Isabel Pereira, et al.
Publicado: (2017)

The Role of Regulatory T Cells and TH17 Cells in Multiple Myeloma
por: Braga, Walter M. T., et al.
Publicado: (2012)

PROTEOMAS: a workflow enabling harmonized proteomic meta-analysis and proteomic signature mapping
por: Bahl, Aileen, et al.
Publicado: (2023)

A microRNA signature profile in EBV(+) diffuse large B-cell lymphoma of the elderly
por: de Andrade, Tathiana Azevedo, et al.
Publicado: (2014)

Biochemical phenotyping of multiple myeloma patients at diagnosis reveals a disorder of mitochondrial complexes I and II and a Hartnup-like disturbance as underlying conditions, also influencing different stages of the disease
por: da Silva, Ismael Dale Cotrim Guerreiro, et al.
Publicado: (2020)

Cancer/Testis Antigen MAGE-C1/CT7: New Target for Multiple Myeloma Therapy
por: de Carvalho, Fabricio, et al.
Publicado: (2012)

May critical molecular cross-talk between indoleamine 2,3-dioxygenase (IDO) and arginase during human aging be targets for immunosenescence control?
por: da Silva, Ismael Dale Cotrim Guerreiro, et al.
Publicado: (2021)

Single-nucleotide variants in TGFB1, TGFBR2, IL17A, and IL17F immune response genes contribute to follicular lymphoma susceptibility and aggressiveness
por: Assis-Mendonça, Guilherme Rossi, et al.
Publicado: (2020)

A computational approach for the discovery of significant cancer genes by weighted mutation and asymmetric spreading strength in networks
por: Cutigi, Jorge Francisco, et al.
Publicado: (2021)

Targeting MAGE-C1/CT7 Expression Increases Cell Sensitivity to the Proteasome Inhibitor Bortezomib in Multiple Myeloma Cell Lines
por: de Carvalho, Fabricio, et al.
Publicado: (2011)

An integrative microenvironment approach for follicular lymphoma: roles of inflammatory cell subsets and immune-response polymorphisms on disease clinical course
por: Assis-Mendonça, Guilherme Rossi, et al.
Publicado: (2020)

Single nucleotide variants in immune-response genes and the tumor microenvironment composition predict progression of mantle cell lymphoma
por: Assis-Mendonça, Guilherme Rossi, et al.
Publicado: (2021)

The treatment of acute lymphoblastic leukemia has come a long way but the best is yet to come
por: Chauffaille, Maria de Lourdes Lopes Ferrari
Publicado: (2013)

Is karyotyping still needed in the diagnosis and monitoring of chronic myeloid leukemia?
por: Chauffaille, Maria de Lourdes L.F.
Publicado: (2017)

EFFECT OF CARBAMIDE PEROXIDE-BASED BLEACHING AGENTS CONTAINING FLUORIDE OR CALCIUM ON TENSILE STRENGTH OF HUMAN ENAMEL
por: Giannini, Marcelo, et al.
Publicado: (2006)

Heart Failure in Menopause: Treatment and New Approaches
por: da Silva, Jaqueline S., et al.
Publicado: (2022)

Transgenerational transmission of trauma and resilience: a qualitative study with Brazilian offspring of Holocaust survivors
por: Braga, Luciana Lorens, et al.
Publicado: (2012)

Limitations of performance status assessment in elderly with acute myeloid leukemia
por: Carbonell, Ana Lúcia Ippolito, et al.
Publicado: (2015)

Editorial: Tumor microenvironment (TME) and tumor immune microenvironment (TIME): New perspectives for prognosis and therapy
por: Ramos, Rodrigo Nalio, et al.
Publicado: (2022)

Differential Transcript Profiles of MHC Class Ib(Qa-1, Qa-2, and Qa-10) and Aire Genes during the Ontogeny of Thymus and Other Tissues
por: Melo-Lima, Breno Luiz, et al.
Publicado: (2014)

A non-canonical peptide synthetase adenylates 3-methyl-2-oxovaleric acid for auriculamide biosynthesis
por: Braga, Daniel, et al.
Publicado: (2016)

Molecular characterization of breast cancer cell lines by clinical immunohistochemical markers
por: Mota, André de Lima, et al.
Publicado: (2017)

JAK2-mutated acute myeloid leukemia: comparison of next-generation sequencing (NGS) and single nucleotide polymorphism array (SNPa) findings between two cases
por: de Noronha, Thiago Rodrigo, et al.
Publicado: (2019)

Additional information offered by single nucleotide polymorphism array advantages in two myelodysplastic syndromes with excess blasts cases and future perspectives
por: Noronha, Thiago Rodrigo de, et al.
Publicado: (2019)

Suppression of citrus canker disease mediated by flagellin perception
por: Andrade, Maxuel de Oliveira, et al.
Publicado: (2023)

Prognostic value of the immunohistochemical expression of vascular endothelial growth factors in malignant salivary gland neoplasms: a systematic review and meta-analysis
por: dos Santos, Erison Santana, et al.
Publicado: (2021)

Role of ADAM10 as a CD30 Sheddase in Classical Hodgkin Lymphoma
por: Hansen, Hinrich P., et al.
Publicado: (2020)

Managing patients with multiple myeloma during the COVID-19 pandemic: recommendations from an expert panel – ABHH monoclonal gammopathies committe
por: Hungria, Vania, et al.
Publicado: (2020)

FMS-related tyrosine kinase 3 internal tandem duplication (FLT3-ITD): a villain among others
por: de Arruda, Vanessa Y.N., et al.
Publicado: (2017)

Autologous stem cell transplantation improves quality of life in economically challenged, Brazilian multiple myeloma patients
por: Etto, Leina Y., et al.
Publicado: (2011)

Shorter ejaculatory abstinence interval and maternal endometrium exposure to seminal plasma as tools to improve pregnancy rate in patients undergoing intracytoplasmic sperm injection cycles
por: Borges Jr., Edson, et al.
Publicado: (2018)

Ethics and IVF add-ons: We need to talk about it
por: Braga, Daniela Paes de Almeida Ferreira, et al.
Publicado: (2022)

When karyotype is decisive for myelodysplastic syndromes diagnosis
por: Perazzio, Aline dos Santos Borgo, et al.
Publicado: (2019)

Identification of MicroRNA Expression Profiles Related to the Aggressiveness of Salivary Gland Adenoid Cystic Carcinomas
por: Zanon, Maicon Fernando, et al.
Publicado: (2023)

Accuracy of microRNAs as markers for the detection of neck lymph node metastases in patients with head and neck squamous cell carcinoma
por: de Carvalho, Ana Carolina, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_gptg81gok461737bn1l90m6iho