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Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection

Lateral flow assay tests are nowadays becoming powerful, low-cost diagnostic tools. Obtaining a result is usually subject to visual interpretation of colored areas on the test by a human operator, introducing subjectivity and the possibility of errors in the extraction of the results. While automate...

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Detalles Bibliográficos
Autores principales: Carrio, Adrian, Sampedro, Carlos, Sanchez-Lopez, Jose Luis, Pimienta, Miguel, Campoy, Pascual
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701349/
https://www.ncbi.nlm.nih.gov/pubmed/26610513
http://dx.doi.org/10.3390/s151129569
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author Carrio, Adrian
Sampedro, Carlos
Sanchez-Lopez, Jose Luis
Pimienta, Miguel
Campoy, Pascual
author_facet Carrio, Adrian
Sampedro, Carlos
Sanchez-Lopez, Jose Luis
Pimienta, Miguel
Campoy, Pascual
author_sort Carrio, Adrian
collection PubMed
description Lateral flow assay tests are nowadays becoming powerful, low-cost diagnostic tools. Obtaining a result is usually subject to visual interpretation of colored areas on the test by a human operator, introducing subjectivity and the possibility of errors in the extraction of the results. While automated test readers providing a result-consistent solution are widely available, they usually lack portability. In this paper, we present a smartphone-based automated reader for drug-of-abuse lateral flow assay tests, consisting of an inexpensive light box and a smartphone device. Test images captured with the smartphone camera are processed in the device using computer vision and machine learning techniques to perform automatic extraction of the results. A deep validation of the system has been carried out showing the high accuracy of the system. The proposed approach, applicable to any line-based or color-based lateral flow test in the market, effectively reduces the manufacturing costs of the reader and makes it portable and massively available while providing accurate, reliable results.
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spelling pubmed-47013492016-01-19 Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection Carrio, Adrian Sampedro, Carlos Sanchez-Lopez, Jose Luis Pimienta, Miguel Campoy, Pascual Sensors (Basel) Article Lateral flow assay tests are nowadays becoming powerful, low-cost diagnostic tools. Obtaining a result is usually subject to visual interpretation of colored areas on the test by a human operator, introducing subjectivity and the possibility of errors in the extraction of the results. While automated test readers providing a result-consistent solution are widely available, they usually lack portability. In this paper, we present a smartphone-based automated reader for drug-of-abuse lateral flow assay tests, consisting of an inexpensive light box and a smartphone device. Test images captured with the smartphone camera are processed in the device using computer vision and machine learning techniques to perform automatic extraction of the results. A deep validation of the system has been carried out showing the high accuracy of the system. The proposed approach, applicable to any line-based or color-based lateral flow test in the market, effectively reduces the manufacturing costs of the reader and makes it portable and massively available while providing accurate, reliable results. MDPI 2015-11-24 /pmc/articles/PMC4701349/ /pubmed/26610513 http://dx.doi.org/10.3390/s151129569 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Carrio, Adrian
Sampedro, Carlos
Sanchez-Lopez, Jose Luis
Pimienta, Miguel
Campoy, Pascual
Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection
title Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection
title_full Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection
title_fullStr Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection
title_full_unstemmed Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection
title_short Automated Low-Cost Smartphone-Based Lateral Flow Saliva Test Reader for Drugs-of-Abuse Detection
title_sort automated low-cost smartphone-based lateral flow saliva test reader for drugs-of-abuse detection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701349/
https://www.ncbi.nlm.nih.gov/pubmed/26610513
http://dx.doi.org/10.3390/s151129569
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