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Lys-315 at the Interfaces of Diagonal Subunits of δ-Crystallin Plays a Critical Role in the Reversibility of Folding and Subunit Assembly
δ-Crystallin is the major structural protein in avian eye lenses and is homologous to the urea cycle enzyme argininosuccinate lyase. This protein is structurally assembled as double dimers. Lys-315 is the only residue which is arranged symmetrically at the diagonal subunit interfaces to interact wit...
Autores principales: | Huang, Chih-Wei, Lin, Hui-Chen, Chou, Chi-Yuan, Kao, Wei-Chuo, Chou, Wei-Yuan, Lee, Hwei-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701392/ https://www.ncbi.nlm.nih.gov/pubmed/26731266 http://dx.doi.org/10.1371/journal.pone.0145957 |
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