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IL-2 / α-IL-2 Complex Treatment Cannot Be Substituted for the Adoptive Transfer of Regulatory T cells to Promote Bone Marrow Engraftment

Cell therapy with recipient Tregs achieves engraftment of allogeneic bone marrow (BM) without the need for cytoreductive conditioning (i.e., without irradiation or cytotoxic drugs). Thereby mixed chimerism and transplantation tolerance are established in recipients conditioned solely with costimulat...

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Detalles Bibliográficos
Autores principales:	Mahr, Benedikt, Unger, Lukas, Hock, Karin, Pilat, Nina, Baranyi, Ulrike, Schwarz, Christoph, Maschke, Svenja, Farkas, Andreas Michael, Wekerle, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701413/ https://www.ncbi.nlm.nih.gov/pubmed/26731275 http://dx.doi.org/10.1371/journal.pone.0146245

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