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Murine Embryonic Stem Cell Plasticity Is Regulated through Klf5 and Maintained by Metalloproteinase MMP1 and Hypoxia

Mouse embryonic stem cells (mESCs) are expanded and maintained pluripotent in vitro in the presence of leukemia inhibitory factor (LIF), an IL6 cytokine family member which displays pleiotropic functions, depending on both cell maturity and cell type. LIF withdrawal leads to heterogeneous differenti...

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Detalles Bibliográficos
Autores principales:	Hammoud, Aya Abou, Kirstein, Nina, Mournetas, Virginie, Darracq, Anais, Broc, Sabine, Blanchard, Camille, Zeineddine, Dana, Mortada, Mohamad, Boeuf, Helene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701481/ https://www.ncbi.nlm.nih.gov/pubmed/26731538 http://dx.doi.org/10.1371/journal.pone.0146281

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