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Time-Course Analysis of Brain Regional Expression Network Responses to Chronic Intermittent Ethanol and Withdrawal: Implications for Mechanisms Underlying Excessive Ethanol Consumption

Long lasting abusive consumption, dependence, and withdrawal are characteristic features of alcohol use disorders (AUD). Mechanistically, persistent changes in gene expression are hypothesized to contribute to brain adaptations leading to ethanol toxicity and AUD. We employed repeated chronic interm...

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Detalles Bibliográficos
Autores principales: Smith, Maren L., Lopez, Marcelo F., Archer, Kellie J., Wolen, Aaron R., Becker, Howard C., Miles, Michael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701666/
https://www.ncbi.nlm.nih.gov/pubmed/26730594
http://dx.doi.org/10.1371/journal.pone.0146257