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Is it really an abscess? An unusual case of metastatic stromal cell sarcoma of the prostate

INTRODUCTION: Prostatic stromal sarcomas account for about 0.1% of all prostatic malignancies. Local recurrence into bladder, seminal vesicles and rectum has been documented. Distal metastasis, has so far only been reported in lung and bone. PRESENTATION OF CASE: We report the case of a 42 year old...

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Autores principales: Wickramasinghe, Shehan, Beenen, Edwin, He, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701799/
https://www.ncbi.nlm.nih.gov/pubmed/26581082
http://dx.doi.org/10.1016/j.ijscr.2015.10.043
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author Wickramasinghe, Shehan
Beenen, Edwin
He, Michael
author_facet Wickramasinghe, Shehan
Beenen, Edwin
He, Michael
author_sort Wickramasinghe, Shehan
collection PubMed
description INTRODUCTION: Prostatic stromal sarcomas account for about 0.1% of all prostatic malignancies. Local recurrence into bladder, seminal vesicles and rectum has been documented. Distal metastasis, has so far only been reported in lung and bone. PRESENTATION OF CASE: We report the case of a 42 year old man with a subcutaneous metastatic deposit of a prostatic stromal cell sarcoma 5 years after radical prostatectomy. Additional staging with CT- and PET-scan showed lymph node involvement in the neck and left axilla. A core biopsy of the skin lesion was undertaken, of which the histology revealed a low grade spindle cell tumour that was morphologically identical to a previously diagnosed prostatic stromal sarcoma. DISCUSSION: In literature distant metastases to the lung and bone have been documented before. This is the first documented case of a subcutaneous metastasis of prostatic stromal cell sarcoma. CONCLUSION: The preferred treatment for prostatic stromal cell sarcoma is surgery by radical prostatectomy or cystoprostatectomy. There is currently not enough literature on the topic to elucidate the role of chemo- or radiotherapy in loco-regional or distant spread.
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spelling pubmed-47017992016-02-03 Is it really an abscess? An unusual case of metastatic stromal cell sarcoma of the prostate Wickramasinghe, Shehan Beenen, Edwin He, Michael Int J Surg Case Rep Case Report INTRODUCTION: Prostatic stromal sarcomas account for about 0.1% of all prostatic malignancies. Local recurrence into bladder, seminal vesicles and rectum has been documented. Distal metastasis, has so far only been reported in lung and bone. PRESENTATION OF CASE: We report the case of a 42 year old man with a subcutaneous metastatic deposit of a prostatic stromal cell sarcoma 5 years after radical prostatectomy. Additional staging with CT- and PET-scan showed lymph node involvement in the neck and left axilla. A core biopsy of the skin lesion was undertaken, of which the histology revealed a low grade spindle cell tumour that was morphologically identical to a previously diagnosed prostatic stromal sarcoma. DISCUSSION: In literature distant metastases to the lung and bone have been documented before. This is the first documented case of a subcutaneous metastasis of prostatic stromal cell sarcoma. CONCLUSION: The preferred treatment for prostatic stromal cell sarcoma is surgery by radical prostatectomy or cystoprostatectomy. There is currently not enough literature on the topic to elucidate the role of chemo- or radiotherapy in loco-regional or distant spread. Elsevier 2015-11-04 /pmc/articles/PMC4701799/ /pubmed/26581082 http://dx.doi.org/10.1016/j.ijscr.2015.10.043 Text en © 2015 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Wickramasinghe, Shehan
Beenen, Edwin
He, Michael
Is it really an abscess? An unusual case of metastatic stromal cell sarcoma of the prostate
title Is it really an abscess? An unusual case of metastatic stromal cell sarcoma of the prostate
title_full Is it really an abscess? An unusual case of metastatic stromal cell sarcoma of the prostate
title_fullStr Is it really an abscess? An unusual case of metastatic stromal cell sarcoma of the prostate
title_full_unstemmed Is it really an abscess? An unusual case of metastatic stromal cell sarcoma of the prostate
title_short Is it really an abscess? An unusual case of metastatic stromal cell sarcoma of the prostate
title_sort is it really an abscess? an unusual case of metastatic stromal cell sarcoma of the prostate
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701799/
https://www.ncbi.nlm.nih.gov/pubmed/26581082
http://dx.doi.org/10.1016/j.ijscr.2015.10.043
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