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STAT-5 Regulates Transcription of the Topoisomerase IIβ-Binding Protein 1 (TopBP1) Gene To Activate the ATR Pathway and Promote Human Papillomavirus Replication

The life cycle of high-risk human papillomaviruses (HPVs) is dependent upon epithelial differentiation. Following infection of basal cells, HPV genomes are stably maintained at low copy numbers, and productive replication or amplification is restricted to highly differentiated suprabasal cells. In h...

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Detalles Bibliográficos
Autores principales:	Hong, Shiyuan, Cheng, Shouqiang, Iovane, Andre, Laimins, Laimonis A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Microbiology 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701836/ https://www.ncbi.nlm.nih.gov/pubmed/26695634 http://dx.doi.org/10.1128/mBio.02006-15

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