Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss

Genome-wide analyses have identified thousands of long noncoding RNAs (lncRNAs). Malat1 (metastasis-associated lung adenocarcinoma transcript 1) is among the most abundant lncRNAs whose expression is altered in numerous cancers. Here we report that genetic loss or systemic knockdown of Malat1 using...

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Detalles Bibliográficos
Autores principales: Arun, Gayatri, Diermeier, Sarah, Akerman, Martin, Chang, Kung-Chi, Wilkinson, J. Erby, Hearn, Stephen, Kim, Youngsoo, MacLeod, A. Robert, Krainer, Adrian R., Norton, Larry, Brogi, Edi, Egeblad, Mikala, Spector, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701977/
https://www.ncbi.nlm.nih.gov/pubmed/26701265
http://dx.doi.org/10.1101/gad.270959.115

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