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Osmotic stress induces the phosphorylation of WNK4 Ser575 via the p38MAPK-MK pathway

The With No lysine [K] (WNK)-Ste20-related proline/alanine-rich kinase (SPAK)/oxidative stress-responsive kinase 1 (OSR1) pathway has been reported to be a crucial signaling pathway for triggering pseudohypoaldosteronism type II (PHAII), an autosomal dominant hereditary disease that is characterized...

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Detalles Bibliográficos
Autores principales: Maruyama, Junichi, Kobayashi, Yumie, Umeda, Tsuyoshi, Vandewalle, Alain, Takeda, Kohsuke, Ichijo, Hidenori, Naguro, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702109/
https://www.ncbi.nlm.nih.gov/pubmed/26732173
http://dx.doi.org/10.1038/srep18710

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