NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity

Nucleolar and spindle-associated protein (NuSAP) is a microtubule-associated protein that functions as a microtubule stabiliser. Depletion of NuSAP leads to severe mitotic defects, however the mechanism by which NuSAP regulates mitosis remains elusive. In this study, we identify the microtubule depo...

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Detalles Bibliográficos
Autores principales: Li, Chenyu, Zhang, Yajun, Yang, Qiaoyun, Ye, Fan, Sun, Stella Ying, Chen, Ee Sin, Liou, Yih-Cherng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702128/
https://www.ncbi.nlm.nih.gov/pubmed/26733216
http://dx.doi.org/10.1038/srep18773

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