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The soluble form of BMPRIB is a novel therapeutic candidate for treating bone related disorders

Bone morphogenetic proteins (BMPs) are multi-functional growth factors that belong to the TGF-beta superfamily. Recently, several soluble BMP receptors, such as ActRIIA-Fc, ActRIIB-Fc, and ALK1-Fc, are undergoing clinical trials. Both BMPRIA and BMPRIB are type I BMP receptors, and while BMPRIA-Fc h...

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Detalles Bibliográficos
Autores principales:	Yamawaki, Kengo, Kondo, Yuichiro, Okada, Tsutomu, Oshima, Takeshi, Kakitani, Makoto, Tomizuka, Kazuma
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702141/ https://www.ncbi.nlm.nih.gov/pubmed/26732094 http://dx.doi.org/10.1038/srep18849

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