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Overexpression of SIRT6 in the hippocampal CA1 impairs the formation of long-term contextual fear memory

Histone modifications have been implicated in learning and memory. Our previous transcriptome data showed that expression of sirtuins 6 (SIRT6), a member of Histone deacetylases (HDACs) family in the hippocampal cornu ammonis 1 (CA1) was decreased after contextual fear conditioning. However, the rol...

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Detalles Bibliográficos
Autores principales:	Yin, Xi, Gao, Yuan, Shi, Hai-Shui, Song, Li, Wang, Jie-Chao, Shao, Juan, Geng, Xu-Hong, Xue, Gai, Li, Jian-Li, Hou, Yan-Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702175/ https://www.ncbi.nlm.nih.gov/pubmed/26732053 http://dx.doi.org/10.1038/srep18982

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