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Intravital imaging of Ca(2+) signals in lymphocytes of Ca(2+) biosensor transgenic mice: indication of autoimmune diseases before the pathological onset

Calcium ion (Ca(2+)) signaling is a typical phenomenon mediated through immune receptors, such as the B-cell antigen receptor (BCR), and it is important for their biological activities. To analyze the signaling of immune receptors together with their in vivo dynamics, we generated stable transgenic...

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Detalles Bibliográficos
Autores principales: Yoshikawa, Soichiro, Usami, Takako, Kikuta, Junichi, Ishii, Masaru, Sasano, Tetsuo, Sugiyama, Koji, Furukawa, Tetsushi, Nakasho, Eiji, Takayanagi, Hiroshi, Tedder, Thomas F., Karasuyama, Hajime, Miyawaki, Atsushi, Adachi, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702216/
https://www.ncbi.nlm.nih.gov/pubmed/26732477
http://dx.doi.org/10.1038/srep18738