Cargando…

N-Heterocyclic Carbene Catalyzed Enantioselective Annulation of Benzothiazolyl Ethyl Acetates with 2-Bromoenals

An N-heterocyclic carbene catalyzed enantioselective [3+3] annulation of benzothiazolyl acetates with 2-bromoenals has been developed. The protocol provides a direct asymmetric synthesis of dihydro-1H-benzothiazolopyridinones in good to very good yields and medium ee values. In many cases, the virtu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ni, Qijian, Xiong, Jiawen, Song, Xiaoxiao, Raabe, Gerhard, Enders, Dieter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702349/ https://www.ncbi.nlm.nih.gov/pubmed/26752810 http://dx.doi.org/10.1055/s-0034-1381004

Ejemplares similares

Asymmetric N-Heterocyclic Carbene Catalyzed Annulation of 2-Alkenylbenzothiazoles with α-Chloro Aldehydes
por: Song, Xiaoxiao, et al.
Publicado: (2014)

Carbene-catalyzed enantioselective annulation of dinucleophilic hydrazones and bromoenals for access to aryl-dihydropyridazinones and related drugs
por: Mondal, Bivas, et al.
Publicado: (2021)

Enantioselective [3+3] atroposelective annulation catalyzed by N-heterocyclic carbenes
por: Zhao, Changgui, et al.
Publicado: (2018)

N-Heterocyclic carbene-catalyzed enantioselective hetero-[10 + 2] annulation
por: Peng, Qiupeng, et al.
Publicado: (2020)

Enantioselective Synthesis of Highly Substituted Fluoroalkylated Benzopyranones and 3-Coumaranones via N-Heterocyclic Carbene-Catalyzed Intramolecular Annulations
por: Barańska, Izabela, et al.
Publicado: (2023)

Regio- and stereoselective synthesis of benzothiazolo-pyrimidinones via an NHC-catalyzed Mannich/lactamization domino reaction
por: Ni, Qijian, et al.
Publicado: (2015)

Enantioselective N-heterocyclic carbene-catalyzed nucleophilic dearomatization of alkyl pyridiniums
por: Flanigan, Darrin M., et al.
Publicado: (2017)

Combining silver- and organocatalysis: an enantioselective sequential catalytic approach towards pyrano-annulated pyrazoles
por: Hack, Daniel, et al.
Publicado: (2015)

C–H activation-annulation on the N-heterocyclic carbene platform
por: Dutta, Champak, et al.
Publicado: (2018)

N-Heterocyclic-Carbene-Catalyzed Domino Reactions via Two or More Activation Modes
por: Chen, Xiang-Yu, et al.
Publicado: (2018)

Access to Spiropyrazolone-butenolides through NHC-Catalyzed [3 + 2]-Asymmetric Annulation of 3-Bromoenals and 1H-Pyrazol-4,5-diones
por: Gil-Ordóñez, Marta, et al.
Publicado: (2023)

N-Heterocyclic carbene-catalyzed oxidative [3 + 2] annulation of dioxindoles and enals: cross coupling of homoenolate and enolate
por: Chen, Xiang-Yu, et al.
Publicado: (2017)

Insights into the Competing Mechanisms and Origin of Enantioselectivity for N-Heterocyclic Carbene-Catalyzed Reaction of Aldehyde with Enamide
por: Qiao, Yan, et al.
Publicado: (2016)

A tandem dearomatization/rearomatization strategy: enantioselective N-heterocyclic carbene-catalyzed α-arylation
por: Wu, Zijun, et al.
Publicado: (2018)

N-Heterocyclic carbene based catalytic platform for Hauser–Kraus annulations
por: Sharique, Mohammed, et al.
Publicado: (2020)

Enantioselective Cyclopropanation Catalyzed by Gold(I)-Carbene Complexes
por: Szabo, Zita, et al.
Publicado: (2022)

Enantioselective S(N)2 Alkylation of Homoenolates by N‐Heterocyclic Carbene Catalysis
por: Li, En, et al.
Publicado: (2023)

Carbene-Catalyzed Atroposelective Annulation for Quick Access to Axially Chiral Thiazine Derivatives
por: Yang, Xiaoqun, et al.
Publicado: (2023)

NHC-Catalyzed Asymmetric Synthesis of Functionalized Succinimides from Enals and α-Ketoamides
por: Wang, Lei, et al.
Publicado: (2015)

Merging Gold and Organocatalysis: A Facile Asymmetric Synthesis of Annulated Pyrroles
por: Hack, Daniel, et al.
Publicado: (2014)

Enantioselective synthesis of planar chiral ferrocenes via palladium-catalyzed annulation with diarylethynes
por: Shi, Yan-Chao, et al.
Publicado: (2013)

Carbene-catalyzed enantioselective oxidative coupling of enals and di(hetero)arylmethanes
por: Chen, Qiao, et al.
Publicado: (2018)

Solid-Phase Synthesis of 2-Benzothiazolyl and 2-(Aminophenyl)benzothiazolyl Amino Acids and Peptides
por: Mourtas, Spyridon, et al.
Publicado: (2023)

A Pd-Catalyzed [4 + 2] Annulation Approach to Fluorinated N-Heterocycles
por: García-Vázquez, Víctor, et al.
Publicado: (2021)

Enantioselective N-Heterocyclic Carbene-Catalyzed β-Hydroxylation of Enals Using Nitroarenes: An Atom Transfer Reaction That Proceeds via Single Electron Transfer
por: White, Nicholas A., et al.
Publicado: (2014)

Preparation of Benzothiazolyl-Decorated Nanoliposomes
por: Mourtas, Spyridon, et al.
Publicado: (2019)

Rhodium-catalyzed enantioselective and diastereodivergent access to diaxially chiral heterocycles
por: Wang, Yishou, et al.
Publicado: (2023)

Phosphine-Catalyzed Enantioselective Intramolecular [3+2] Annulations To Generate Fused Ring Systems
por: Lee, Sarah Yunmi, et al.
Publicado: (2015)

N-Heterocyclic carbenes
por: Nolan, Steven P
Publicado: (2015)

N‐Heterocyclic Carbene Organocatalysis: With or Without Carbenes?
por: Gehrke, Sascha, et al.
Publicado: (2020)

Iridium/N-heterocyclic carbene-catalyzed C–H borylation of arenes by diisopropylaminoborane
por: Tobisu, Mamoru, et al.
Publicado: (2016)

N‐Heterocyclic Carbene Catalyzed Photoenolization/Diels–Alder Reaction of Acid Fluorides
por: Mavroskoufis, Andreas, et al.
Publicado: (2020)

N-Heterocyclic carbene iron complexes catalyze the ring-opening polymerization of lactide
por: Nylund, Pamela V. S., et al.
Publicado: (2022)

π-Extension of heterocycles via a Pd-catalyzed heterocyclic aryne annulation: π-extended donors for TADF emitters
por: Spence, Katie A., et al.
Publicado: (2022)

Enantioselective S(N)2 Alkylation of Homoenolates by N‐Heterocyclic Carbene Catalysis (Adv. Sci. 29/2023)
por: Li, En, et al.
Publicado: (2023)

Gold-catalyzed (4 + 2)-annulations between α-alkyl alkenylgold carbenes and benzisoxazoles with reactive alkyl groups
por: Mokar, Bhanudas Dattatray, et al.
Publicado: (2018)

Copper-catalyzed [3+3] annulation of ketones with oxime acetates for the synthesis of pyridines
por: Li, Yilin, et al.
Publicado: (2022)

Organocatalytic activation of isocyanides: N-heterocyclic carbene-catalyzed enaminone synthesis from ketones
por: Kim, Jungwon, et al.
Publicado: (2017)

N-Heterocyclic Carbene-Catalyzed Random Copolymerization of N-Carboxyanhydrides of α-Amino Acids
por: Eom, Kuen Hee, et al.
Publicado: (2021)

N-Heterocyclic carbene-catalyzed deaminative cross-coupling of aldehydes with Katritzky pyridinium salts
por: Kim, Inwon, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_5bq0224sdd88d55afuc59ondfo