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Suppressed diversity of survivin splicing in active rheumatoid arthritis

INTRODUCTION: Alternative splicing distinguishes normal and pathologic cells. High levels of oncoprotein survivin recognise patients with severe rheumatoid arthritis (RA). Here, we assess clinical relevance of alternative splicing of survivin in leukocytes of peripheral blood (PBMC) and bone marrow...

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Detalles Bibliográficos
Autores principales: Turkkila, Minna, Andersson, Karin M.E., Amu, Sylvie, Brisslert, Mikael, Erlandsson, Malin C., Silfverswärd, Sofia, Bokarewa, Maria I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702383/
https://www.ncbi.nlm.nih.gov/pubmed/26160473
http://dx.doi.org/10.1186/s13075-015-0689-z