Mesenchymal adenomatous polyposis coli plays critical and diverse roles in regulating lung development

BACKGROUND: Adenomatous polyposis coli (Apc) is a tumor suppressor that inhibits Wnt/Ctnnb1. Mutations of Apc will not only lead to familial adenomatous polyposis with associated epithelial lesions, but will also cause aggressive fibromatosis in mesenchymal cells. However, the roles of Apc in regula...

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Detalles Bibliográficos
Autores principales: Luo, Yongfeng, El Agha, Elie, Turcatel, Gianluca, Chen, Hui, Chiu, Joanne, Warburton, David, Bellusci, Saverio, Qian, Bang-Ping, Menke, Douglas B., Shi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702410/
https://www.ncbi.nlm.nih.gov/pubmed/26092405
http://dx.doi.org/10.1186/s12915-015-0153-1

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