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Structure/Function Studies Involving the V3 Region of the HIV-1 Envelope Delineate Multiple Factors That Affect Neutralization Sensitivity

Antibodies (Abs) specific for the V3 loop of the HIV-1 gp120 envelope neutralize most tier 1 and many tier 2 viruses and are present in essentially all HIV-infected individuals as well as immunized humans and animals. Vaccine-induced V3 Abs are associated with reduced HIV infection rates in humans a...

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Detalles Bibliográficos
Autores principales:	Zolla-Pazner, Susan, Cohen, Sandra Sharpe, Boyd, David, Kong, Xiang-Peng, Seaman, Michael, Nussenzweig, Michel, Klein, Florian, Overbaugh, Julie, Totrov, Max
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2015
Materias:	Pathogenesis and Immunity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702699/ https://www.ncbi.nlm.nih.gov/pubmed/26491157 http://dx.doi.org/10.1128/JVI.01645-15

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