Microscopic Observation Drug Susceptibility Assay for Rapid Diagnosis of Lymph Node Tuberculosis and Detection of Drug Resistance

In this study, 132 patients with lymphadenopathy were investigated. Fifty-two (39.4%) were diagnosed with tuberculosis (TB). The microscopic observation drug susceptibility (MODS) assay provided rapid (13 days), accurate diagnosis (sensitivity, 65.4%) and reliable drug susceptibility testing (DST)....

Descripción completa

Detalles Bibliográficos
Autores principales: Kirwan, Daniela E., Ugarte-Gil, Cesar, Gilman, Robert H., Caviedes, Luz, Rizvi, Hasan, Ticona, Eduardo, Chavez, Gonzalo, Cabrera, José Luis, Matos, Eduardo D., Evans, Carlton A., Moore, David A. J., Friedland, Jon S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Mycobacteriology and Aerobic Actinomycetes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702711/
https://www.ncbi.nlm.nih.gov/pubmed/26511739
http://dx.doi.org/10.1128/JCM.02227-15
Descripción
Sumario:In this study, 132 patients with lymphadenopathy were investigated. Fifty-two (39.4%) were diagnosed with tuberculosis (TB). The microscopic observation drug susceptibility (MODS) assay provided rapid (13 days), accurate diagnosis (sensitivity, 65.4%) and reliable drug susceptibility testing (DST). Despite its lower sensitivity than that of other methods, its faster results and simultaneous DST are advantageous in resource-poor settings, supporting the incorporation of MODS into diagnostic algorithms for extrapulmonary TB.

Ejemplares similares