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SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis
To understand living cells, we need knowledge of each of their parts as well as about the interactions of these parts. To gain rapid and comprehensive access to this information, annotation databases are required. Here, we present SubtiWiki 2.0, the integrated database for the model bacterium Bacill...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702770/ https://www.ncbi.nlm.nih.gov/pubmed/26433225 http://dx.doi.org/10.1093/nar/gkv1006 |
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author | Michna, Raphael H. Zhu, Bingyao Mäder, Ulrike Stülke, Jörg |
author_facet | Michna, Raphael H. Zhu, Bingyao Mäder, Ulrike Stülke, Jörg |
author_sort | Michna, Raphael H. |
collection | PubMed |
description | To understand living cells, we need knowledge of each of their parts as well as about the interactions of these parts. To gain rapid and comprehensive access to this information, annotation databases are required. Here, we present SubtiWiki 2.0, the integrated database for the model bacterium Bacillus subtilis (http://subtiwiki.uni-goettingen.de/). SubtiWiki provides text-based access to published information about the genes and proteins of B. subtilis as well as presentations of metabolic and regulatory pathways. Moreover, manually curated protein-protein interactions diagrams are linked to the protein pages. Finally, expression data are shown with respect to gene expression under 104 different conditions as well as absolute protein quantification for cytoplasmic proteins. To facilitate the mobile use of SubtiWiki, we have now expanded it by Apps that are available for iOS and Android devices. Importantly, the App allows to link private notes and pictures to the gene/protein pages. Today, SubtiWiki has become one of the most complete collections of knowledge on a living organism in one single resource. |
format | Online Article Text |
id | pubmed-4702770 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-47027702016-01-07 SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis Michna, Raphael H. Zhu, Bingyao Mäder, Ulrike Stülke, Jörg Nucleic Acids Res Database Issue To understand living cells, we need knowledge of each of their parts as well as about the interactions of these parts. To gain rapid and comprehensive access to this information, annotation databases are required. Here, we present SubtiWiki 2.0, the integrated database for the model bacterium Bacillus subtilis (http://subtiwiki.uni-goettingen.de/). SubtiWiki provides text-based access to published information about the genes and proteins of B. subtilis as well as presentations of metabolic and regulatory pathways. Moreover, manually curated protein-protein interactions diagrams are linked to the protein pages. Finally, expression data are shown with respect to gene expression under 104 different conditions as well as absolute protein quantification for cytoplasmic proteins. To facilitate the mobile use of SubtiWiki, we have now expanded it by Apps that are available for iOS and Android devices. Importantly, the App allows to link private notes and pictures to the gene/protein pages. Today, SubtiWiki has become one of the most complete collections of knowledge on a living organism in one single resource. Oxford University Press 2016-01-04 2015-10-03 /pmc/articles/PMC4702770/ /pubmed/26433225 http://dx.doi.org/10.1093/nar/gkv1006 Text en © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Database Issue Michna, Raphael H. Zhu, Bingyao Mäder, Ulrike Stülke, Jörg SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis |
title | SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis |
title_full | SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis |
title_fullStr | SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis |
title_full_unstemmed | SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis |
title_short | SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis |
title_sort | subtiwiki 2.0—an integrated database for the model organism bacillus subtilis |
topic | Database Issue |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702770/ https://www.ncbi.nlm.nih.gov/pubmed/26433225 http://dx.doi.org/10.1093/nar/gkv1006 |
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