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SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis

To understand living cells, we need knowledge of each of their parts as well as about the interactions of these parts. To gain rapid and comprehensive access to this information, annotation databases are required. Here, we present SubtiWiki 2.0, the integrated database for the model bacterium Bacill...

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Detalles Bibliográficos
Autores principales: Michna, Raphael H., Zhu, Bingyao, Mäder, Ulrike, Stülke, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702770/
https://www.ncbi.nlm.nih.gov/pubmed/26433225
http://dx.doi.org/10.1093/nar/gkv1006
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author Michna, Raphael H.
Zhu, Bingyao
Mäder, Ulrike
Stülke, Jörg
author_facet Michna, Raphael H.
Zhu, Bingyao
Mäder, Ulrike
Stülke, Jörg
author_sort Michna, Raphael H.
collection PubMed
description To understand living cells, we need knowledge of each of their parts as well as about the interactions of these parts. To gain rapid and comprehensive access to this information, annotation databases are required. Here, we present SubtiWiki 2.0, the integrated database for the model bacterium Bacillus subtilis (http://subtiwiki.uni-goettingen.de/). SubtiWiki provides text-based access to published information about the genes and proteins of B. subtilis as well as presentations of metabolic and regulatory pathways. Moreover, manually curated protein-protein interactions diagrams are linked to the protein pages. Finally, expression data are shown with respect to gene expression under 104 different conditions as well as absolute protein quantification for cytoplasmic proteins. To facilitate the mobile use of SubtiWiki, we have now expanded it by Apps that are available for iOS and Android devices. Importantly, the App allows to link private notes and pictures to the gene/protein pages. Today, SubtiWiki has become one of the most complete collections of knowledge on a living organism in one single resource.
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spelling pubmed-47027702016-01-07 SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis Michna, Raphael H. Zhu, Bingyao Mäder, Ulrike Stülke, Jörg Nucleic Acids Res Database Issue To understand living cells, we need knowledge of each of their parts as well as about the interactions of these parts. To gain rapid and comprehensive access to this information, annotation databases are required. Here, we present SubtiWiki 2.0, the integrated database for the model bacterium Bacillus subtilis (http://subtiwiki.uni-goettingen.de/). SubtiWiki provides text-based access to published information about the genes and proteins of B. subtilis as well as presentations of metabolic and regulatory pathways. Moreover, manually curated protein-protein interactions diagrams are linked to the protein pages. Finally, expression data are shown with respect to gene expression under 104 different conditions as well as absolute protein quantification for cytoplasmic proteins. To facilitate the mobile use of SubtiWiki, we have now expanded it by Apps that are available for iOS and Android devices. Importantly, the App allows to link private notes and pictures to the gene/protein pages. Today, SubtiWiki has become one of the most complete collections of knowledge on a living organism in one single resource. Oxford University Press 2016-01-04 2015-10-03 /pmc/articles/PMC4702770/ /pubmed/26433225 http://dx.doi.org/10.1093/nar/gkv1006 Text en © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Issue
Michna, Raphael H.
Zhu, Bingyao
Mäder, Ulrike
Stülke, Jörg
SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis
title SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis
title_full SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis
title_fullStr SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis
title_full_unstemmed SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis
title_short SubtiWiki 2.0—an integrated database for the model organism Bacillus subtilis
title_sort subtiwiki 2.0—an integrated database for the model organism bacillus subtilis
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702770/
https://www.ncbi.nlm.nih.gov/pubmed/26433225
http://dx.doi.org/10.1093/nar/gkv1006
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