Cargando…

KLIFS: a structural kinase-ligand interaction database

Protein kinases play a crucial role in cell signaling and are important drug targets in several therapeutic areas. The KLIFS database contains detailed structural kinase-ligand interaction information derived from all (>2900) structures of catalytic domains of human and mouse protein kinases depo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kooistra, Albert J., Kanev, Georgi K., van Linden, Oscar P.J., Leurs, Rob, de Esch, Iwan J.P., de Graaf, Chris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Database Issue
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702798/ https://www.ncbi.nlm.nih.gov/pubmed/26496949 http://dx.doi.org/10.1093/nar/gkv1082

Ejemplares similares

KLIFS: an overhaul after the first 5 years of supporting kinase research
por: Kanev, Georgi K, et al.
Publicado: (2020)

Predicting the target landscape of kinase inhibitors using 3D convolutional neural networks
por: Kanev, Georgi K., et al.
Publicado: (2023)

Function-specific virtual screening for GPCR ligands using a combined scoring method
por: Kooistra, Albert J., et al.
Publicado: (2016)

The G protein database, GproteinDb
por: Pándy-Szekeres, Gáspár, et al.
Publicado: (2021)

GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources
por: Pándy-Szekeres, Gáspár, et al.
Publicado: (2022)

BitterDB: taste ligands and receptors database in 2019
por: Dagan-Wiener, Ayana, et al.
Publicado: (2019)

The MHC Motif Atlas: a database of MHC binding specificities and ligands
por: Tadros, Daniel M, et al.
Publicado: (2022)

mutLBSgeneDB: mutated ligand binding site gene DataBase
por: Kim, Pora, et al.
Publicado: (2017)

sc-PDB: a 3D-database of ligandable binding sites—10 years on
por: Desaphy, Jérémy, et al.
Publicado: (2014)

Structural Analysis of Chemokine Receptor–Ligand Interactions
por: Arimont, Marta, et al.
Publicado: (2017)

Platinum: a database of experimentally measured effects of mutations on structurally defined protein–ligand complexes
por: Pires, Douglas E.V., et al.
Publicado: (2014)

Nucleotide binding database NBDB – a collection of sequence motifs with specific protein-ligand interactions
por: Zheng, Zejun, et al.
Publicado: (2016)

Mouse Phenome Database: an integrative database and analysis suite for curated empirical phenotype data from laboratory mice
por: Bogue, Molly A, et al.
Publicado: (2018)

Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans
por: Choi, Jarny, et al.
Publicado: (2019)

G4LDB 2.2: a database for discovering and studying G-quadruplex and i-Motif ligands
por: Wang, Yu-Huan, et al.
Publicado: (2021)

Identification of novel α7 nicotinic receptor ligands by in silico screening against the crystal structure of a chimeric α7 receptor ligand binding domain
por: Akdemir, Atilla, et al.
Publicado: (2012)

STCRDab: the structural T-cell receptor database
por: Leem, Jinwoo, et al.
Publicado: (2018)

ValidatorDB: database of up-to-date validation results for ligands and non-standard residues from the Protein Data Bank
por: Sehnal, David, et al.
Publicado: (2014)

UniLectin3D, a database of carbohydrate binding proteins with curated information on 3D structures and interacting ligands
por: Bonnardel, François, et al.
Publicado: (2019)

KinaseMD: kinase mutations and drug response database
por: Hu, Ruifeng, et al.
Publicado: (2020)

The MAR databases: development and implementation of databases specific for marine metagenomics
por: Klemetsen, Terje, et al.
Publicado: (2018)

The 2018 Nucleic Acids Research database issue and the online molecular biology database collection
por: Rigden, Daniel J, et al.
Publicado: (2018)

GPCRdb in 2021: integrating GPCR sequence, structure and function
por: Kooistra, Albert J, et al.
Publicado: (2020)

3D‐e‐Chem: Structural Cheminformatics Workflows for Computer‐Aided Drug Discovery
por: Kooistra, Albert J., et al.
Publicado: (2018)

The 2016 database issue of Nucleic Acids Research and an updated molecular biology database collection
por: Rigden, Daniel J., et al.
Publicado: (2016)

The ChEMBL database in 2017
por: Gaulton, Anna, et al.
Publicado: (2017)

In Silico Veritas: The Pitfalls and Challenges of Predicting GPCR-Ligand Interactions
por: Roumen, Luc, et al.
Publicado: (2011)

The GOA database: Gene Ontology annotation updates for 2015
por: Huntley, Rachael P., et al.
Publicado: (2014)

Thera-SAbDab: the Therapeutic Structural Antibody Database
por: Raybould, Matthew I J, et al.
Publicado: (2020)

The Comparative Toxicogenomics Database: update 2019
por: Davis, Allan Peter, et al.
Publicado: (2019)

The Comparative Toxicogenomics Database: update 2017
por: Davis, Allan Peter, et al.
Publicado: (2017)

PRRDB: A comprehensive database of Pattern-Recognition Receptors and their ligands
por: Lata, Sneh, et al.
Publicado: (2008)

Mouse genome database 2016
por: Bult, Carol J., et al.
Publicado: (2016)

Mouse Phenome Database: a data repository and analysis suite for curated primary mouse phenotype data
por: Bogue, Molly A, et al.
Publicado: (2020)

Human Ageing Genomic Resources: new and updated databases
por: Tacutu, Robi, et al.
Publicado: (2018)

IPD-IMGT/HLA Database
por: Robinson, James, et al.
Publicado: (2020)

The MEROPS database of proteolytic enzymes, their substrates and inhibitors in 2017 and a comparison with peptidases in the PANTHER database
por: Rawlings, Neil D, et al.
Publicado: (2018)

Comparative Toxicogenomics Database (CTD): update 2021
por: Davis, Allan Peter, et al.
Publicado: (2020)

The IPD-IMGT/HLA Database
por: Barker, Dominic J, et al.
Publicado: (2022)

Expanded national database collection and data coverage in the FINDbase worldwide database for clinically relevant genomic variation allele frequencies
por: Viennas, Emmanouil, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_fd83ttmk85qmpflu4aenq4psi2