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The Transporter Classification Database (TCDB): recent advances

The Transporter Classification Database (TCDB; http://www.tcdb.org) is a freely accessible reference database for transport protein research, which provides structural, functional, mechanistic, evolutionary and disease/medical information about transporters from organisms of all types. TCDB is the o...

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Autores principales: Saier, Milton H., Reddy, Vamsee S., Tsu, Brian V., Ahmed, Muhammad Saad, Li, Chun, Moreno-Hagelsieb, Gabriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702804/
https://www.ncbi.nlm.nih.gov/pubmed/26546518
http://dx.doi.org/10.1093/nar/gkv1103
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author Saier, Milton H.
Reddy, Vamsee S.
Tsu, Brian V.
Ahmed, Muhammad Saad
Li, Chun
Moreno-Hagelsieb, Gabriel
author_facet Saier, Milton H.
Reddy, Vamsee S.
Tsu, Brian V.
Ahmed, Muhammad Saad
Li, Chun
Moreno-Hagelsieb, Gabriel
author_sort Saier, Milton H.
collection PubMed
description The Transporter Classification Database (TCDB; http://www.tcdb.org) is a freely accessible reference database for transport protein research, which provides structural, functional, mechanistic, evolutionary and disease/medical information about transporters from organisms of all types. TCDB is the only transport protein classification database adopted by the International Union of Biochemistry and Molecular Biology (IUBMB). It consists of more than 10 000 non-redundant transport systems with more than 11 000 reference citations, classified into over 1000 transporter families. Transporters in TCDB can be single or multi-component systems, categorized in a functional/phylogenetic hierarchical system of classes, subclasses, families, subfamilies and transport systems. TCDB also includes updated software designed to analyze the distinctive features of transport proteins, extending its usefulness. Here we present a comprehensive update of the database contents and features and summarize recent discoveries recorded in TCDB.
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spelling pubmed-47028042016-01-07 The Transporter Classification Database (TCDB): recent advances Saier, Milton H. Reddy, Vamsee S. Tsu, Brian V. Ahmed, Muhammad Saad Li, Chun Moreno-Hagelsieb, Gabriel Nucleic Acids Res Database Issue The Transporter Classification Database (TCDB; http://www.tcdb.org) is a freely accessible reference database for transport protein research, which provides structural, functional, mechanistic, evolutionary and disease/medical information about transporters from organisms of all types. TCDB is the only transport protein classification database adopted by the International Union of Biochemistry and Molecular Biology (IUBMB). It consists of more than 10 000 non-redundant transport systems with more than 11 000 reference citations, classified into over 1000 transporter families. Transporters in TCDB can be single or multi-component systems, categorized in a functional/phylogenetic hierarchical system of classes, subclasses, families, subfamilies and transport systems. TCDB also includes updated software designed to analyze the distinctive features of transport proteins, extending its usefulness. Here we present a comprehensive update of the database contents and features and summarize recent discoveries recorded in TCDB. Oxford University Press 2016-01-04 2015-11-05 /pmc/articles/PMC4702804/ /pubmed/26546518 http://dx.doi.org/10.1093/nar/gkv1103 Text en © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Database Issue
Saier, Milton H.
Reddy, Vamsee S.
Tsu, Brian V.
Ahmed, Muhammad Saad
Li, Chun
Moreno-Hagelsieb, Gabriel
The Transporter Classification Database (TCDB): recent advances
title The Transporter Classification Database (TCDB): recent advances
title_full The Transporter Classification Database (TCDB): recent advances
title_fullStr The Transporter Classification Database (TCDB): recent advances
title_full_unstemmed The Transporter Classification Database (TCDB): recent advances
title_short The Transporter Classification Database (TCDB): recent advances
title_sort transporter classification database (tcdb): recent advances
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702804/
https://www.ncbi.nlm.nih.gov/pubmed/26546518
http://dx.doi.org/10.1093/nar/gkv1103
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