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SynLethDB: synthetic lethality database toward discovery of selective and sensitive anticancer drug targets
Synthetic lethality (SL) is a type of genetic interaction between two genes such that simultaneous perturbations of the two genes result in cell death or a dramatic decrease of cell viability, while a perturbation of either gene alone is not lethal. SL reflects the biologically endogenous difference...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702809/ https://www.ncbi.nlm.nih.gov/pubmed/26516187 http://dx.doi.org/10.1093/nar/gkv1108 |