Cargando…

Mouse genome database 2016

The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the primary community model organism database for the laboratory mouse and serves as the source for key biological reference data related to mouse genes, gene functions, phenotypes and disease models with a strong emphasis on the rel...

Descripción completa

Detalles Bibliográficos
Autores principales: Bult, Carol J., Eppig, Janan T., Blake, Judith A., Kadin, James A., Richardson, Joel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702860/
https://www.ncbi.nlm.nih.gov/pubmed/26578600
http://dx.doi.org/10.1093/nar/gkv1211
_version_ 1782408666867040256
author Bult, Carol J.
Eppig, Janan T.
Blake, Judith A.
Kadin, James A.
Richardson, Joel E.
author_facet Bult, Carol J.
Eppig, Janan T.
Blake, Judith A.
Kadin, James A.
Richardson, Joel E.
author_sort Bult, Carol J.
collection PubMed
description The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the primary community model organism database for the laboratory mouse and serves as the source for key biological reference data related to mouse genes, gene functions, phenotypes and disease models with a strong emphasis on the relationship of these data to human biology and disease. As the cost of genome-scale sequencing continues to decrease and new technologies for genome editing become widely adopted, the laboratory mouse is more important than ever as a model system for understanding the biological significance of human genetic variation and for advancing the basic research needed to support the emergence of genome-guided precision medicine. Recent enhancements to MGD include new graphical summaries of biological annotations for mouse genes, support for mobile access to the database, tools to support the annotation and analysis of sets of genes, and expanded support for comparative biology through the expansion of homology data.
format Online
Article
Text
id pubmed-4702860
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-47028602016-01-07 Mouse genome database 2016 Bult, Carol J. Eppig, Janan T. Blake, Judith A. Kadin, James A. Richardson, Joel E. Nucleic Acids Res Database Issue The Mouse Genome Database (MGD; http://www.informatics.jax.org) is the primary community model organism database for the laboratory mouse and serves as the source for key biological reference data related to mouse genes, gene functions, phenotypes and disease models with a strong emphasis on the relationship of these data to human biology and disease. As the cost of genome-scale sequencing continues to decrease and new technologies for genome editing become widely adopted, the laboratory mouse is more important than ever as a model system for understanding the biological significance of human genetic variation and for advancing the basic research needed to support the emergence of genome-guided precision medicine. Recent enhancements to MGD include new graphical summaries of biological annotations for mouse genes, support for mobile access to the database, tools to support the annotation and analysis of sets of genes, and expanded support for comparative biology through the expansion of homology data. Oxford University Press 2016-01-04 2015-11-17 /pmc/articles/PMC4702860/ /pubmed/26578600 http://dx.doi.org/10.1093/nar/gkv1211 Text en © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Database Issue
Bult, Carol J.
Eppig, Janan T.
Blake, Judith A.
Kadin, James A.
Richardson, Joel E.
Mouse genome database 2016
title Mouse genome database 2016
title_full Mouse genome database 2016
title_fullStr Mouse genome database 2016
title_full_unstemmed Mouse genome database 2016
title_short Mouse genome database 2016
title_sort mouse genome database 2016
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702860/
https://www.ncbi.nlm.nih.gov/pubmed/26578600
http://dx.doi.org/10.1093/nar/gkv1211
work_keys_str_mv AT bultcarolj mousegenomedatabase2016
AT eppigjanant mousegenomedatabase2016
AT blakejuditha mousegenomedatabase2016
AT kadinjamesa mousegenomedatabase2016
AT richardsonjoele mousegenomedatabase2016
AT mousegenomedatabase2016