Biocuration of functional annotation at the European nucleotide archive

The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is a repository for the submission, maintenance and presentation of nucleotide sequence data and related sample and experimental information. In this article we report on ENA in 2015 regarding general activity, notable published data se...

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Detalles Bibliográficos
Autores principales: Gibson, Richard, Alako, Blaise, Amid, Clara, Cerdeño-Tárraga, Ana, Cleland, Iain, Goodgame, Neil, ten Hoopen, Petra, Jayathilaka, Suran, Kay, Simon, Leinonen, Rasko, Liu, Xin, Pallreddy, Swapna, Pakseresht, Nima, Rajan, Jeena, Rosselló, Marc, Silvester, Nicole, Smirnov, Dmitriy, Toribio, Ana Luisa, Vaughan, Daniel, Zalunin, Vadim, Cochrane, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Database Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702917/
https://www.ncbi.nlm.nih.gov/pubmed/26615190
http://dx.doi.org/10.1093/nar/gkv1311
Descripción
Sumario:The European Nucleotide Archive (ENA; http://www.ebi.ac.uk/ena) is a repository for the submission, maintenance and presentation of nucleotide sequence data and related sample and experimental information. In this article we report on ENA in 2015 regarding general activity, notable published data sets and major achievements. This is followed by a focus on sustainable biocuration of functional annotation, an area which has particularly felt the pressure of sequencing growth. The importance of functional annotation, how it can be submitted and the shifting role of the biocurator in the context of increasing volumes of data are all discussed.

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