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HTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT)

Human T-cell leukemia virus type 1 (HTLV-1) infects CD4(+) T cells and induces proliferation of infected cells in vivo, which leads to the onset of adult T-cell leukemia (ATL) in some infected individuals. The HTLV-1 bZIP factor (HBZ) gene, which is encoded in the minus strand of HTLV-1, plays criti...

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Detalles Bibliográficos
Autores principales:	Yasuma, Keiko, Yasunaga, Jun-ichirou, Takemoto, Keiko, Sugata, Kenji, Mitobe, Yuichi, Takenouchi, Norihiro, Nakagawa, Masanori, Suzuki, Yutaka, Matsuoka, Masao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703212/ https://www.ncbi.nlm.nih.gov/pubmed/26735971 http://dx.doi.org/10.1371/journal.ppat.1005372

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