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PXR Mediated Protection against Liver Inflammation by Ginkgolide A in Tetrachloromethane Treated Mice

The pregnane X receptor (PXR), a liver and intestine specific receptor,, has been reported to be related with the repression of inflammation as well as activation of cytochromosome P450 3A (CYP3A) expression. We examined the effect of PXR on tetrachloromethane (CCl4)-induced mouse liver inflammation...

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Detalles Bibliográficos
Autores principales: Ye, Nanhui, Wang, Hang, Hong, Jing, Zhang, Tao, Lin, Chaotong, Meng, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703351/
https://www.ncbi.nlm.nih.gov/pubmed/26759700
http://dx.doi.org/10.4062/biomolther.2015.077