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Interferon Alpha Signalling and Its Relevance for the Upregulatory Effect of Transporter Proteins Associated with Antigen Processing (TAP) in Patients with Malignant Melanoma
INTRODUCTION: Interferon alpha (IFNα) is routinely used in the clinical practice for adjuvant systemic melanoma therapy. Understanding the molecular mechanism of IFNα effects and prediction of response in the IFNα therapy regime allows initiation and continuation of IFNα treatment for responder and...
Autores principales: | Heise, Ruth, Amann, Philipp M., Ensslen, Silke, Marquardt, Yvonne, Czaja, Katharina, Joussen, Sylvia, Beer, Daniel, Abele, Rupert, Plewnia, Gabriele, Tampé, Robert, Merk, Hans F., Hermanns, Heike M., Baron, Jens M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703378/ https://www.ncbi.nlm.nih.gov/pubmed/26735690 http://dx.doi.org/10.1371/journal.pone.0146325 |
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