Conformational Sampling and Binding Site Assessment of Suppression of Tumorigenicity 2 Ectodomain

Suppression of Tumorigenicity 2 (ST2), a member of the interleukin-1 receptor (IL-1R) family, activates type 2 immune responses to pathogens and tissue damage via binding to IL-33. Dysregulated responses contribute to asthma, graft-versus-host and autoinflammatory diseases and disorders. To study ST...

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Detalles Bibliográficos
Autores principales: Yang, Chao-Yie, Delproposto, James, Chinnaswamy, Krishnapriya, Brown, William Clay, Wang, Shuying, Stuckey, Jeanne A., Wang, Xinquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703388/
https://www.ncbi.nlm.nih.gov/pubmed/26735493
http://dx.doi.org/10.1371/journal.pone.0146522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703388/
https://www.ncbi.nlm.nih.gov/pubmed/26735493
http://dx.doi.org/10.1371/journal.pone.0146522

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