HER Specific TKIs Exert Their Antineoplastic Effects on Breast Cancer Cell Lines through the Involvement of STAT5 and JNK

BACKGROUND: HER-targeted tyrosine kinase inhibitors (TKIs) have demonstrated pro-apoptotic and antiproliferative effects in vitro and in vivo. The exact pathways through which TKIs exert their antineoplastic effects are, however, still not completely understood. METHODS: Using Milliplex assays, we h...

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Detalles Bibliográficos
Autores principales: Gschwantler-Kaulich, Daphne, Grunt, Thomas W., Muhr, Daniela, Wagner, Renate, Kölbl, Heinz, Singer, Christian F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703392/
https://www.ncbi.nlm.nih.gov/pubmed/26735495
http://dx.doi.org/10.1371/journal.pone.0146311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703392/
https://www.ncbi.nlm.nih.gov/pubmed/26735495
http://dx.doi.org/10.1371/journal.pone.0146311

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