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Normal and Fibrotic Rat Livers Demonstrate Shear Strain Softening and Compression Stiffening: A Model for Soft Tissue Mechanics
Tissues including liver stiffen and acquire more extracellular matrix with fibrosis. The relationship between matrix content and stiffness, however, is non-linear, and stiffness is only one component of tissue mechanics. The mechanical response of tissues such as liver to physiological stresses is n...
Autores principales: | Perepelyuk, Maryna, Chin, LiKang, Cao, Xuan, van Oosten, Anne, Shenoy, Vivek B., Janmey, Paul A., Wells, Rebecca G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703410/ https://www.ncbi.nlm.nih.gov/pubmed/26735954 http://dx.doi.org/10.1371/journal.pone.0146588 |
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