Cargando…

Coarse-Grained Simulations of Topology-Dependent Mechanisms of Protein Unfolding and Translocation Mediated by ClpY ATPase Nanomachines

Clp ATPases are powerful ring shaped nanomachines which participate in the degradation pathway of the protein quality control system, coupling the energy from ATP hydrolysis to threading substrate proteins (SP) through their narrow central pore. Repetitive cycles of sequential intra-ring ATP hydroly...

Descripción completa

Detalles Bibliográficos
Autores principales: Kravats, Andrea N., Tonddast-Navaei, Sam, Stan, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703411/
https://www.ncbi.nlm.nih.gov/pubmed/26734937
http://dx.doi.org/10.1371/journal.pcbi.1004675