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Chromosomal Instability and Phosphoinositide Pathway Gene Signatures in Glioblastoma Multiforme
Structural rearrangements of chromosome 10 are frequently observed in glioblastoma multiforme and over 80 % of tumour samples archived in the catalogue of somatic mutations in cancer database had gene copy number loss for PI4K2A which encodes phosphatidylinositol 4-kinase type IIalpha. PI4K2A loss o...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703635/ https://www.ncbi.nlm.nih.gov/pubmed/25502460 http://dx.doi.org/10.1007/s12035-014-9034-9 |