Are Clade Specific HIV Vaccines a Necessity? An Analysis Based on Mathematical Models

As HIV-1 envelope immune responses are critical to vaccine related protection, most candidate HIV vaccines entering efficacy trials are based upon a clade specific design. This need for clade specific vaccine prototypes markedly reduces the implementation of potentially effective HIV vaccines. We ut...

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Detalles Bibliográficos
Autores principales: Dimitrov, Dobromir, Kublin, James G., Ramsey, Scott, Corey, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703729/
https://www.ncbi.nlm.nih.gov/pubmed/26844286
http://dx.doi.org/10.1016/j.ebiom.2015.11.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703729/
https://www.ncbi.nlm.nih.gov/pubmed/26844286
http://dx.doi.org/10.1016/j.ebiom.2015.11.009

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