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Are Clade Specific HIV Vaccines a Necessity? An Analysis Based on Mathematical Models
As HIV-1 envelope immune responses are critical to vaccine related protection, most candidate HIV vaccines entering efficacy trials are based upon a clade specific design. This need for clade specific vaccine prototypes markedly reduces the implementation of potentially effective HIV vaccines. We ut...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703729/ https://www.ncbi.nlm.nih.gov/pubmed/26844286 http://dx.doi.org/10.1016/j.ebiom.2015.11.009 |